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RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca(2+) release
RACK1 is not a G protein but closely resembles the heterotrimeric Gβ-subunit. RACK1 serves as a scaffold, linking protein kinase C to its substrates. We demonstrate that RACK1 physiologically binds inositol 1,4,5-trisphosphate receptors and regulates Ca(2+) release by enhancing inositol 1,4,5-trisph...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC356950/ https://ncbi.nlm.nih.gov/pubmed/14983009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308567100 |
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