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Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca(2+) release via locally derived NADH
NADH regulates the release of calcium from the endoplasmic reticulum by modulation of inositol 1,4,5-trisphosphate receptors (IP(3)R), accounting for the augmented calcium release of hypoxic cells. We report selective binding of IP(3)R to GAPDH, whose activity leads to the local generation of NADH t...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2005
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547892/ https://ncbi.nlm.nih.gov/pubmed/15677321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409657102 |
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