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Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca(2+) release via locally derived NADH
NADH regulates the release of calcium from the endoplasmic reticulum by modulation of inositol 1,4,5-trisphosphate receptors (IP(3)R), accounting for the augmented calcium release of hypoxic cells. We report selective binding of IP(3)R to GAPDH, whose activity leads to the local generation of NADH t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547892/ https://ncbi.nlm.nih.gov/pubmed/15677321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409657102 |
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