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Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo

Acute exposure of cells in culture to high NaCl damages DNA and impairs its repair. However, after several hours of cell cycle arrest, cells multiply in the hypertonic medium. Here, we show that, although adapted cells proliferate rapidly and do not become apoptotic, they nevertheless contain numero...

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Detalhes bibliográficos
Main Authors: Dmitrieva, Natalia I., Cai, Qi, Burg, Maurice B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356948/
https://ncbi.nlm.nih.gov/pubmed/14983007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308463100
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