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DNA double-strand breaks induced by high NaCl occur predominantly in gene deserts

High concentration of NaCl increases DNA breaks both in cell culture and in vivo. The breaks remain elevated as long as NaCl concentration remains high and are rapidly repaired when the concentration is lowered. The exact nature of the breaks, and their location, has not been entirely clear, and it...

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Hlavní autoři: Dmitrieva, Natalia I., Cui, Kairong, Kitchaev, Daniil A., Zhao, Keji, Burg, Maurice B.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251130/
https://ncbi.nlm.nih.gov/pubmed/22106305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114677108
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