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Knockout of Ku86 accelerates cellular senescence induced by high NaCl
NaCl induces DNA breaks, thus leading to cellular senescence. Here we showed that Ku86 deficiency accelerated the high NaCl-induced cellular senescence. We find that 1) high NaCl induces rapid cellular senescence in Ku86 deficient (xrs5) cells, 2) Ku86 deficiency shortens lifespan of C. elegans in h...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783634/ https://ncbi.nlm.nih.gov/pubmed/19946467 |
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