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Ku86 preserves chromatin integrity in cells adapted to high NaCl

Cells adapted to high NaCl have many DNA breaks both in cell culture and in the renal inner medulla in vivo; yet they survive, function, and even proliferate. Here, we show that Ku86 is important for maintaining chromosomal integrity despite the continued presence of DNA breaks. The Ku heterodimer i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Dmitrieva, Natalia I., Celeste, Arkady, Nussenzweig, André, Burg, Maurice B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180807/
https://ncbi.nlm.nih.gov/pubmed/16027367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504870102
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