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Ku86 preserves chromatin integrity in cells adapted to high NaCl
Cells adapted to high NaCl have many DNA breaks both in cell culture and in the renal inner medulla in vivo; yet they survive, function, and even proliferate. Here, we show that Ku86 is important for maintaining chromosomal integrity despite the continued presence of DNA breaks. The Ku heterodimer i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180807/ https://ncbi.nlm.nih.gov/pubmed/16027367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504870102 |
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