Lack of the Matricellular Protein SPARC (Secreted Protein, Acidic and Rich in Cysteine) Attenuates Liver Fibrogenesis in Mice

INTRODUCTION: Secreted Protein, Acidic and Rich in Cysteine (SPARC) is a matricellular protein involved in many biological processes and found over-expressed in cirrhotic livers. By mean of a genetic approach we herein provide evidence from different in vivo liver disease models suggesting a profibr...

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Hauptverfasser: Atorrasagasti, Catalina, Peixoto, Estanislao, Aquino, Jorge B., Kippes, Néstor, Malvicini, Mariana, Alaniz, Laura, Garcia, Mariana, Piccioni, Flavia, Fiore, Esteban J., Bayo, Juan, Bataller, Ramón, Guruceaga, Elizabeth, Corrales, Fernando, Podhajcer, Osvaldo, Mazzolini, Guillermo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569438/
https://ncbi.nlm.nih.gov/pubmed/23408952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054962
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