Expression of TP53 Isoforms p53β or p53γ Enhances Chemosensitivity in TP53(null) Cell Lines

The carboxy-terminal truncated p53 alternative spliced isoforms, p53β and p53γ, are expressed at disparate levels in cancer and are suggested to influence treatment response and therapy outcome. However, their functional role in cancer remains to be elucidated. We investigated their individual funct...

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Main Authors: Silden, Elisabeth, Hjelle, Sigrun M., Wergeland, Line, Sulen, André, Andresen, Vibeke, Bourdon, Jean-Christophe, Micklem, David R., McCormack, Emmet, Gjertsen, Bjørn Tore
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569410/
https://ncbi.nlm.nih.gov/pubmed/23409163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056276
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