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Expression of TP53 Isoforms p53β or p53γ Enhances Chemosensitivity in TP53(null) Cell Lines

The carboxy-terminal truncated p53 alternative spliced isoforms, p53β and p53γ, are expressed at disparate levels in cancer and are suggested to influence treatment response and therapy outcome. However, their functional role in cancer remains to be elucidated. We investigated their individual funct...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Silden, Elisabeth, Hjelle, Sigrun M., Wergeland, Line, Sulen, André, Andresen, Vibeke, Bourdon, Jean-Christophe, Micklem, David R., McCormack, Emmet, Gjertsen, Bjørn Tore
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569410/
https://ncbi.nlm.nih.gov/pubmed/23409163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056276
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