Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

In addition to the tumor suppressor p53 protein, also termed p53α, the TP53 gene produces p53β and p53γ through alternative splicing of exons 9β and 9γ located within TP53 intron 9. Here we report that both TG003, a specific inhibitor of Cdc2-like kinases (Clk) that regulates the alternative splicin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Marcel, V, Fernandes, K, Terrier, O, Lane, D P, Bourdon, J-C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131182/
https://ncbi.nlm.nih.gov/pubmed/24926616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.73
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados