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Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation

The aim of this study was to design, develop, and optimize respirable tacrolimus microparticles and nanoparticles and multifunctional tacrolimus lung surfactant mimic particles for targeted dry powder inhalation delivery as a pulmonary nanomedicine. Particles were rationally designed and produced at...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Xiao, Hayes, Don, Zwischenberger, Joseph B, Kuhn, Robert J, Mansour, Heidi M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569053/
https://ncbi.nlm.nih.gov/pubmed/23403805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S40166
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