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Small Molecule Ligands for Active Targeting of TrkC-Expressing Tumor Cells

[Image: see text] A small molecule motif was used in “active targeting” to deliver cytotoxic substances into tumor cells that express the TrkC receptor. Underlying this study was the hypothesis that internalization of targeted conjugates into cells would be facile if mediated by receptor binding and...

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Autores principales: Ko, Eunhwa, Kamkaew, Anyanee, Burgess, Kevin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2012
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568983/
https://ncbi.nlm.nih.gov/pubmed/23411915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300227d
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