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Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
Alpha-synucleinopathies (ASP) are neurodegenerative disorders, characterized by accumulation of misfolded α-synuclein, selective neuronal loss, and extensive gliosis. It is accepted that microgliosis and astrogliosis contribute to the disease progression in ASP. Toll-like receptors (TLRs) are expres...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568908/ https://ncbi.nlm.nih.gov/pubmed/23108585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22437 |
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