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The B7-independent isoform of CTLA-4 functions to regulate autoimmune diabetes
The critical role of cytotoxic lymphocyte antigen 4 (CTLA-4) in inhibiting antigen-driven T cell responses upon engagement with its ligands, B7-1 and B7-2, and its importance for peripheral T cell tolerance and T cell homeostasis has been studied intensively. The CTLA-4 splice variant, li-CTLA-4 is...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568535/ https://ncbi.nlm.nih.gov/pubmed/23293354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201362 |
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