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Correlated Evolution of Positions within Mammalian cis Elements
Transcriptional regulation critically depends on proper interactions between transcription factors (TF) and their cognate DNA binding sites. The widely used model of TF-DNA binding – the Positional Weight Matrix (PWM) – presumes independence between positions within the binding site. However, there...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568137/ https://ncbi.nlm.nih.gov/pubmed/23408994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055521 |
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