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Correlated Evolution of Nucleotide Positions within Splice Sites in Mammals

Splice sites (SSs)—short nucleotide sequences flanking introns—are under selection for spliceosome binding, and adhere to consensus sequences. However, non-consensus nucleotides, many of which probably reduce SS performance, are frequent. Little is known about the mechanisms maintaining such apparen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Denisov, Stepan, Bazykin, Georgii, Favorov, Alexander, Mironov, Andrey, Gelfand, Mikhail
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671708/
https://ncbi.nlm.nih.gov/pubmed/26642327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144388
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