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Position and distance specificity are important determinants of cis-regulatory motifs in addition to evolutionary conservation
Computational discovery of cis-regulatory elements remains challenging. To cope with the high false positives, evolutionary conservation is routinely used. However, conservation is only one of the attributes of cis-regulatory elements and is neither necessary nor sufficient. Here, we assess two addi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904283/ https://ncbi.nlm.nih.gov/pubmed/17452354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm201 |
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