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Position and distance specificity are important determinants of cis-regulatory motifs in addition to evolutionary conservation

Computational discovery of cis-regulatory elements remains challenging. To cope with the high false positives, evolutionary conservation is routinely used. However, conservation is only one of the attributes of cis-regulatory elements and is neither necessary nor sufficient. Here, we assess two addi...

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Bibliografiset tiedot
Päätekijät: Vardhanabhuti, Saran, Wang, Junwen, Hannenhalli, Sridhar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904283/
https://ncbi.nlm.nih.gov/pubmed/17452354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm201
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