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Conservation in first introns is positively associated with the number of exons within genes and the presence of regulatory epigenetic signals
BACKGROUND: Genomes of higher eukaryotes have surprisingly long first introns and in some cases, the first introns have been shown to have higher conservation relative to other introns. However, the functional relevance of conserved regions in the first introns is poorly understood. Leveraging the r...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085337/ https://ncbi.nlm.nih.gov/pubmed/24964727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-526 |
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