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Conservation in first introns is positively associated with the number of exons within genes and the presence of regulatory epigenetic signals

BACKGROUND: Genomes of higher eukaryotes have surprisingly long first introns and in some cases, the first introns have been shown to have higher conservation relative to other introns. However, the functional relevance of conserved regions in the first introns is poorly understood. Leveraging the r...

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Detalhes bibliográficos
Main Authors: Park, Seung Gu, Hannenhalli, Sridhar, Choi, Sun Shim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085337/
https://ncbi.nlm.nih.gov/pubmed/24964727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-526
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