Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

Inflammasomes are multi-protein complexes that trigger the activation of caspase-1 and the maturation of interleukin-1β (IL-1β), yet the regulation of these complexes remains poorly characterized. Here we show that nitric oxide (NO) inhibited the NLRP3-mediated ASC pyroptosome formation, caspase-1 a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Mao, Kairui, Chen, Shuzhen, Chen, Mingkuan, Ma, Yonglei, Wang, Yan, Huang, Bo, He, Zhengyu, Zeng, Yan, Hu, Yu, Sun, Shuhui, Li, Jing, Wu, Xiaodong, Wang, Xiangrui, Strober, Warren, Chen, Chang, Meng, Guangxun, Sun, Bing
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567828/
https://ncbi.nlm.nih.gov/pubmed/23318584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.6
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker