Curcumin Suppresses Soluble Tau Dimers and Corrects Molecular Chaperone, Synaptic, and Behavioral Deficits in Aged Human Tau Transgenic Mice

The mechanisms underlying Tau-related synaptic and cognitive deficits and the interrelationships between Tau species, their clearance pathways, and synaptic impairments remain poorly understood. To gain insight into these mechanisms, we examined these interrelationships in aged non-mutant genomic hu...

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Detalhes bibliográficos
Main Authors: Ma, Qiu-Lan, Zuo, Xiaohong, Yang, Fusheng, Ubeda, Oliver J., Gant, Dana J., Alaverdyan, Mher, Teng, Edmond, Hu, Shuxin, Chen, Ping-Ping, Maiti, Panchanan, Teter, Bruce, Cole, Greg M., Frautschy, Sally A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567657/
https://ncbi.nlm.nih.gov/pubmed/23264626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393751
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