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Molecular Chaperone Dysfunction in Neurodegenerative Diseases and Effects of Curcumin

The intra- and extracellular accumulation of misfolded and aggregated amyloid proteins is a common feature in several neurodegenerative diseases, which is thought to play a major role in disease severity and progression. The principal machineries maintaining proteostasis are the ubiquitin proteasoma...

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Bibliografiske detaljer
Main Authors: Maiti, Panchanan, Manna, Jayeeta, Veleri, Shobi, Frautschy, Sally
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217372/
https://ncbi.nlm.nih.gov/pubmed/25386560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/495091
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