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Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars compacta and subsequent reduction of dopamine levels in striatum are associated with motor deficits that characterize Parkinson’s disease (PD). In addition, half of the PD patients also exhibit frontostriatal-mediate...

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Detalles Bibliográficos
Publicado en:Transl Neurodegener
Main Authors: Maiti, Panchanan, Manna, Jayeeta, Dunbar, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655877/
https://ncbi.nlm.nih.gov/pubmed/29090092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-017-0099-z
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