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Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars compacta and subsequent reduction of dopamine levels in striatum are associated with motor deficits that characterize Parkinson’s disease (PD). In addition, half of the PD patients also exhibit frontostriatal-mediate...

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Maiti, Panchanan, Manna, Jayeeta, Dunbar, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655877/
https://ncbi.nlm.nih.gov/pubmed/29090092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-017-0099-z
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