Yes-associated Protein Isoform 1 (Yap1) Promotes Cardiomyocyte Survival and Growth to Protect against Myocardial Ischemic Injury

Yap1 is an important regulator of cardiomyocyte proliferation and embryonic heart development, yet the function of endogenous Yap1 in the adult heart remains unknown. We studied the role of Yap1 in maintaining basal cardiac function and in modulating injury after chronic myocardial infarction (MI)....

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Autors principals: Del Re, Dominic P., Yang, Yanfei, Nakano, Noritsugu, Cho, Jaeyeaon, Zhai, Peiyong, Yamamoto, Takanobu, Zhang, Nailing, Yabuta, Norikazu, Nojima, Hiroshi, Pan, Duojia, Sadoshima, Junichi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567650/
https://ncbi.nlm.nih.gov/pubmed/23275380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.436311
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