Modelling the evolution of genetic instability during tumour progression

The role of genetic instability in driving carcinogenesis remains controversial. Genetic instability should accelerate carcinogenesis by increasing the rate of advantageous driver mutations; however, genetic instability can also potentially retard tumour growth by increasing the rate of deleterious...

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Detaylı Bibliyografya
Asıl Yazarlar: S Datta, Ruchira, Gutteridge, Alice, Swanton, Charles, Maley, Carlo C, Graham, Trevor A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2013
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567468/
https://ncbi.nlm.nih.gov/pubmed/23396531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.12024
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