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Identification and characterization of small molecule inhibitors of a PHD finger()
A number of histone-binding domains are implicated in cancer through improper binding of chromatin. In a clinically reported case of acute myeloid leukemia (AML), a genetic fusion protein between nucleoporin 98 and the third plant homeodomain (PHD) finger of JARID1A drives an oncogenic transcription...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567257/ https://ncbi.nlm.nih.gov/pubmed/22994852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3009278 |
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