Resveratrol depletes mitochondrial DNA and inhibition of autophagy enhances resveratrol-induced caspase activation

We recently demonstrated that resveratrol induces caspase-dependent apoptosis in multiple cancer cell types. Whether apoptosis is also regulated by other cell death mechanisms such as autophagy is not clearly defined. Here we show that inhibition of autophagy enhanced resveratrol-induced caspase act...

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Détails bibliographiques
Auteurs principaux: Prabhu, Varun, Srivastava, Pragya, Yadav, Neelu, Amadori, Michael, Schneider, Andrea, Seshadri, Athul, Pitaressi, Jason, Scott, Rachael, Zhang, Honghao, Koochekpour, Shahriar, Gogada, Raghu, Chandra, Dhyan
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567227/
https://ncbi.nlm.nih.gov/pubmed/23088850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2012.10.010
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