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Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis

Previous studies have demonstrated that curcumin induces mitochondria-mediated apoptosis. However, understanding of the molecular mechanisms underlying curcumin-induced cell death remains limited. In this study, we demonstrate that curcumin treatment of cancer cells caused dose- and time-dependent c...

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Main Authors: Gogada, Raghu, Amadori, Michael, Zhang, Honghao, Jones, Anthony, Verone, Alissa, Pitarresi, Jason, Jandhyam, Sirisha, Prabhu, Varun, Black, Jennifer D, Chandra, Dhyan
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272293/
https://ncbi.nlm.nih.gov/pubmed/22101335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.23.18292
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