Resveratrol depletes mitochondrial DNA and inhibition of autophagy enhances resveratrol-induced caspase activation

We recently demonstrated that resveratrol induces caspase-dependent apoptosis in multiple cancer cell types. Whether apoptosis is also regulated by other cell death mechanisms such as autophagy is not clearly defined. Here we show that inhibition of autophagy enhanced resveratrol-induced caspase act...

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Detalhes bibliográficos
Main Authors: Prabhu, Varun, Srivastava, Pragya, Yadav, Neelu, Amadori, Michael, Schneider, Andrea, Seshadri, Athul, Pitaressi, Jason, Scott, Rachael, Zhang, Honghao, Koochekpour, Shahriar, Gogada, Raghu, Chandra, Dhyan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567227/
https://ncbi.nlm.nih.gov/pubmed/23088850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2012.10.010
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