Resveratrol Induces p53-independent, X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Bax Protein Oligomerization on Mitochondria to Initiate Cytochrome c Release and Caspase Activation

Resveratrol, a naturally occurring phytoalexin, is known to induce apoptosis in multiple cancer cell types, but the underlying molecular mechanisms remain unclear. Here, we show that resveratrol induced p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated translocation of Bax to...

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Detalhes bibliográficos
Main Authors: Gogada, Raghu, Prabhu, Varun, Amadori, Michael, Scott, Rachael, Hashmi, Sana, Chandra, Dhyan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190683/
https://ncbi.nlm.nih.gov/pubmed/21712378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.202440
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