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Apaf-1- and Caspase-8-independent apoptosis

Two major apoptosis pathways, the mitochondrial and death receptor pathways, are well recognized. Here we established cell lines from the fetal thymus of Apaf-1-, Caspase-9-, or Bax/Bak-deficient mice. These cell lines were resistant to apoptosis induced by DNA-damaging agents, RNA or protein synthe...

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Detalhes bibliográficos
Main Authors: Imao, T, Nagata, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554337/
https://ncbi.nlm.nih.gov/pubmed/23197294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.149
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