Altered Cohesin Gene Dosage Affects Mammalian Meiotic Chromosome Structure and Behavior

Based on studies in mice and humans, cohesin loss from chromosomes during the period of protracted meiotic arrest appears to play a major role in chromosome segregation errors during female meiosis. In mice, mutations in meiosis-specific cohesin genes cause meiotic disturbances and infertility. Howe...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Murdoch, Brenda, Owen, Nichole, Stevense, Michelle, Smith, Helen, Nagaoka, So, Hassold, Terry, McKay, Michael, Xu, Huiling, Fu, Jun, Revenkova, Ekaterina, Jessberger, Rolf, Hunt, Patricia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2013
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567145/
https://ncbi.nlm.nih.gov/pubmed/23408896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003241
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