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Cohesin expression restricted to the pre-dictyate stages of oocyte development provides full fertility and prevents aneuploidy

To ensure correct meiotic chromosome segregation, sister chromatid cohesion (SCC) needs to be maintained from its establishment in prophase I oocytes before birth until continuation of meiosis into metaphase II upon oocyte maturation in the adult. Aging human oocytes suffer a steep increase in chrom...

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Detalhes bibliográficos
Main Authors: Revenkova, Ekaterina, Herrmann, Kathleen, Adelfalk, Caroline, Jessberger, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945217/
https://ncbi.nlm.nih.gov/pubmed/20817531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.08.024
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