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Cohesin expression restricted to the pre-dictyate stages of oocyte development provides full fertility and prevents aneuploidy
To ensure correct meiotic chromosome segregation, sister chromatid cohesion (SCC) needs to be maintained from its establishment in prophase I oocytes before birth until continuation of meiosis into metaphase II upon oocyte maturation in the adult. Aging human oocytes suffer a steep increase in chrom...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945217/ https://ncbi.nlm.nih.gov/pubmed/20817531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.08.024 |
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