Altered Cohesin Gene Dosage Affects Mammalian Meiotic Chromosome Structure and Behavior

Based on studies in mice and humans, cohesin loss from chromosomes during the period of protracted meiotic arrest appears to play a major role in chromosome segregation errors during female meiosis. In mice, mutations in meiosis-specific cohesin genes cause meiotic disturbances and infertility. Howe...

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Detalhes bibliográficos
Main Authors: Murdoch, Brenda, Owen, Nichole, Stevense, Michelle, Smith, Helen, Nagaoka, So, Hassold, Terry, McKay, Michael, Xu, Huiling, Fu, Jun, Revenkova, Ekaterina, Jessberger, Rolf, Hunt, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567145/
https://ncbi.nlm.nih.gov/pubmed/23408896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003241
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