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IRX-2, a Novel Immunotherapeutic, Enhances Functions of Human Dendritic Cells
BACKGROUND: In a recent phase II clinical trial for HNSCC patients, IRX-2, a cell-derived biologic, promoted T-cell infiltration into the tumor and prolonged overall survival. Mechanisms responsible for these IRX-2-mediated effects are unknown. We hypothesized that IRX-2 enhanced tumor antigen-(TA)-...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567103/ https://ncbi.nlm.nih.gov/pubmed/23408925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047234 |
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