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Phenotypic and functional characteristics of ATP-hydrolysing CD4(+)CD39(+) FOXP3(+) and CD4(+)CD39(+)FOXP3(neg)T-cell subsets in patients with cancer

Human CD4(+)CD39(+) regulatory T (Treg) cells hydrolyze exogenous ATP and participate in immunosuppressive adenosine production. They contain two T-cell subsets whose role in mediating suppression is not understood. Frequencies of both CD4(+)CD39(+) subsets were evaluated in peripheral blood lymphoc...

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Detalhes bibliográficos
Main Authors: Schuler, Patrick J., Schilling, Bastian, Harasymczuk, Malgorzata, Hoffmann, Thomas, Johnson, Jonas, Lang, Stephan, Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689271/
https://ncbi.nlm.nih.gov/pubmed/22585562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142347
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