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Human Circulating CD4(+)CD25(high)Foxp3(+)Regulatory T Cells Kill Autologous CD8(+)but Not CD4(+)Responder Cells by Fas-Mediated Apoptosis()

Mechanisms utilized by human regulatory T cells (Treg) for elimination of effector cells may vary. We investigated the possibility that the mechanism of Treg suppression depends on Fas/FasL-mediated apoptosis of responder cells (RC). CD4(+)CD25(high)Foxp3(+)Treg and autologous CD4(+)CD25(−) and CD8(...

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Detalhes bibliográficos
Main Authors: Strauss, Laura, Bergmann, Christoph, Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721355/
https://ncbi.nlm.nih.gov/pubmed/19155494
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