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Phenotypic and functional characteristics of ATP-hydrolysing CD4(+)CD39(+) FOXP3(+) and CD4(+)CD39(+)FOXP3(neg)T-cell subsets in patients with cancer
Human CD4(+)CD39(+) regulatory T (Treg) cells hydrolyze exogenous ATP and participate in immunosuppressive adenosine production. They contain two T-cell subsets whose role in mediating suppression is not understood. Frequencies of both CD4(+)CD39(+) subsets were evaluated in peripheral blood lymphoc...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689271/ https://ncbi.nlm.nih.gov/pubmed/22585562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142347 |
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