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IRX-2, a novel biologic, favors the expansion of T effector over T regulatory cells in a human tumor microenvironment model

IRX-2, a natural cytokine biological with multiple components, has been used in preclinical and clinical studies to promote antitumor activity of T lymphocytes. To define cellular mechanisms responsible for antitumor effects of IRX-2, its ability to induce effector T cells (Teff) was examined in a m...

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Detalhes bibliográficos
Main Authors: Schilling, Bastian, Harasymczuk, Malgorzata, Schuler, Patrick, Egan, James E., Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268969/
https://ncbi.nlm.nih.gov/pubmed/21915712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0813-8
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