Candidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea

BACKGROUND: Fetal hemoglobin level is a heritable complex trait that strongly correlates swith the clinical severity of sickle cell disease. Only few genetic loci have been identified as robustly associated with fetal hemoglobin in patients with sickle cell disease, primarily adults. The sole approv...

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Главные авторы: Green, Nancy S., Ender, Katherine L., Pashankar, Farzana, Driscoll, Catherine, Giardina, Patricia J., Mullen, Craig A., Clark, Lorraine N., Manwani, Deepa, Crotty, Jennifer, Kisselev, Sergey, Neville, Kathleen A., Hoppe, Carolyn, Barral, Sandra
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567082/
https://ncbi.nlm.nih.gov/pubmed/23409025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055709
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