Candidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea

BACKGROUND: Fetal hemoglobin level is a heritable complex trait that strongly correlates swith the clinical severity of sickle cell disease. Only few genetic loci have been identified as robustly associated with fetal hemoglobin in patients with sickle cell disease, primarily adults. The sole approv...

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Detalhes bibliográficos
Main Authors: Green, Nancy S., Ender, Katherine L., Pashankar, Farzana, Driscoll, Catherine, Giardina, Patricia J., Mullen, Craig A., Clark, Lorraine N., Manwani, Deepa, Crotty, Jennifer, Kisselev, Sergey, Neville, Kathleen A., Hoppe, Carolyn, Barral, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567082/
https://ncbi.nlm.nih.gov/pubmed/23409025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055709
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