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Interconverting Conformations of Slipped-DNA Junctions Formed by Trinucleotide Repeats Affect Repair Outcome
[Image: see text] Expansions of (CTG)·(CAG) repeated DNAs are the mutagenic cause of 14 neurological diseases, likely arising through the formation and processing of slipped-strand DNAs. These transient intermediates of repeat length mutations are formed by out-of-register mispairing of repeat units...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical
Society
2013
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566650/ https://ncbi.nlm.nih.gov/pubmed/23339280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301369b |
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