Chaperone-like Activity of High-Mobility Group Box 1 Protein and Its Role in Reducing the Formation of Polyglutamine Aggregates

High-mobility group box 1 protein (HMGB1), which mainly exists in the nucleus, has recently been shown to function as a sentinel molecule for viral nucleic acid sensing and an autophagy regulator in the cytoplasm. In this study, we studied the chaperone-like activity of HMGB1 and found that HMGB1 in...

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Hlavní autoři: Min, Hyun Jin, Ko, Eun Ae, Wu, Jie, Kim, Eun Sung, Kwon, Min Kyung, Kwak, Man Sup, Choi, Ji Eun, Lee, Jong Eun, Shin, Jeon-Soo
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2013
Témata:
Molecular and Structural Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566580/
https://ncbi.nlm.nih.gov/pubmed/23303669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202472
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