High-Mobility Group Box 1-Induced Complement Activation Causes Sterile Inflammation

High-mobility group box 1 (HMGB1), a well-known danger-associated molecular pattern molecule, acts as a pro-inflammatory molecule when secreted by activated immune cells or released after necrotic cell damage. HMGB1 binds to immunogenic bacterial components and augments septic inflammation. In this...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kim, Sook Young, Son, Myoungsun, Lee, Sang Eun, Park, In Ho, Kwak, Man Sup, Han, Myeonggil, Lee, Hyun Sook, Kim, Eun Sook, Kim, Jae-Young, Lee, Jong Eun, Choi, Ji Eun, Diamond, Betty, Shin, Jeon-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904255/
https://ncbi.nlm.nih.gov/pubmed/29696019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00705
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