Sulfatide Inhibits HMGB1 Secretion by Hindering Toll-Like Receptor 4 Localization Within Lipid Rafts

The high mobility group box 1 (HMGB1) is a well-known late mediator of sepsis, secreted by multiple stimuli, involving pathways, such as the mitogen-activated protein kinase (MAPK) and nuclear factor kappa B (NF-κB) pathways, and reactive oxygen species (ROS) under inflammation. Sulfatide, in contra...

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Опубликовано в: :Front Immunol
Главные авторы: Kim, Hee Sue, Han, Myeonggil, Park, In Ho, Park, Cheol Ho, Kwak, Man Sup, Shin, Jeon-Soo
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324676/
https://ncbi.nlm.nih.gov/pubmed/32655573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01305
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