Peroxiredoxin-mediated disulfide bond formation is required for nucleocytoplasmic translocation and secretion of HMGB1 in response to inflammatory stimuli

The nuclear protein HMGB1 (high mobility group box 1) is secreted by monocytes-macrophages in response to inflammatory stimuli and serves as a danger-associated molecular pattern. Acetylation and phosphorylation of HMGB1 are implicated in the regulation of its nucleocytoplasmic translocation for sec...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Kwak, Man Sup, Kim, Hee Sue, Lkhamsuren, Khulan, Kim, Young Hun, Han, Myeong Gil, Shin, Jae Min, Park, In Ho, Rhee, Woo Joong, Lee, Se Kyoung, Rhee, Sue Goo, Shin, Jeon-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482348/
https://ncbi.nlm.nih.gov/pubmed/31026770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101203
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