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Modeling the Assembly of the Multiple Domains of α-actinin-4 and Its Role in Actin Cross-linking

The assembly of proteins into multidomain complexes is critical for their function. In eukaryotic nonmuscle cells, regulation of the homodimeric actin cross-linking protein α-actinin-4 (ACTN4) during cell migration involves signaling receptors with intrinsic tyrosine kinase activity, yet the underly...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Travers, Timothy, Shao, Hanshuang, Wells, Alan, Camacho, Carlos J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566466/
https://ncbi.nlm.nih.gov/pubmed/23442921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.003
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