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Phosphorylation of α-Actinin 4 upon Epidermal Growth Factor Exposure Regulates Its Interaction with Actin

The ubiquitously expressed family of α-actinins bridges actin filaments to stabilize adhesions, a process disrupted during growth factor-induced migration of cells. During the dissolution of the actin cytoskeleton, actinins are phosphorylated on tyrosines, although the consequences of this are unkno...

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Autors principals: Shao, Hanshuang, Wu, Chuanyue, Wells, Alan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807316/
https://ncbi.nlm.nih.gov/pubmed/19920151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035790
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