Sorcin modulates mitochondrial Ca(2+) handling and reduces apoptosis in neonatal rat cardiac myocytes

Sorcin localizes in cellular membranes and has been demonstrated to modulate cytosolic Ca(2+) handling in cardiac myocytes. Sorcin also localizes in mitochondria; however, the effect of sorcin on mitochondrial Ca(2+) handling is unknown. Using mitochondrial pericam, we measured mitochondrial Ca(2+)...

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Hauptverfasser: Suarez, Jorge, McDonough, Patrick M., Scott, Brian T., Suarez-Ramirez, Angelica, Wang, Hong, Fricovsky, Eduardo S., Dillmann, Wolfgang H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566440/
https://ncbi.nlm.nih.gov/pubmed/23151801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00039.2012
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